66 patients with ruptured lateral ligaments were treated surgically and then given Aniflazym (serrapeptase) to study it’s effectiveness in reducing post-operative swelling.

In the group receiving the serrapeptase, swelling was down by 50% on the third day post-surgery.  In the control groups, no reduction in swelling was seen.

Since swelling is what causes most of the pain, those patients receiving serrapeptase were pain free quicker than those that did not receive the enzyme.

The researchers concluded that serrapeptase was more effective in reducing post-operative swelling than traditional conservative measures like bed rest, raised legs and the application of ice.

Reference:

Reduction of postoperative swelling. Objective measurement of swelling of the upper ankle joint in treatment with serrapeptase– a prospective study.

Esch PM, Gerngross H, Fabian A.

Fortschr Med. 1989 Feb 10;107(4):67-8, 71-2. German.