What is the Correct Dosage of Serrapeptase? 9

medicine-bottles-and-pills-close-up-What's the right amount of serrapeptase to take every day? Some manufacturers don't make it easy to figure out how much serratiopeptidase is actually in a product. The medical literature usually refers to “SU,” or serratiopeptidase units. This is a measure of how much fibrin protein a unit of the problem can break down. And some of the best manufacturers measure the products in “IU,” or international units. These units are difficult to translate into milligrams, because enzymes are measured by the amount of work they do, not their mass.

The very lowest dose of serratiopeptidase that will usually get a response in children is about 10,000 IU. The very lowest dose that will usually get a response in adults is about 20,000 IU. Some products offer about 40,000 IU, while the best brands usually contain about 80,000 IU in every pill. It all gets a little confusing. But if you go with brands you trust (click here to see the serrapeptase products I trust – I have used serrapeptase products from this manufacturer for years), you can just make sure you take one dose a day rather than worrying about milligrams, SU, or IU. Don't take more than the manufacturer recommends.

I recommend that you either use enteric-coated serrapeptase (serratiopeptidase) products; the enteric coating keeps the enzyme from being destroyed by acid in the stomach so it arrives intact in the small intestine to be absorbed into the bloodstream.

And never leave serratiopeptidase in your car on a summer day. The interiors of cars heat quickly, and just 15 minutes at 55° C (132° F) will ruin the product.

About Andy

I suffered a serious neck injury when I was about 19 years old. That problem didn't affect me until I was in my 40s, but I then suffered two prolapsed discs in my neck and problems with my right arm and hand. Serrapeptase was recommended by my chiropractor to try to break up the scar tissue around the vertebrae that were causing me the problems. It seemed to help me with my problem, so created this site to help inform people what serrapeptase is, what it can do and just as importantly, what it cannot do. I hope you find the information useful.

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9 thoughts on “What is the Correct Dosage of Serrapeptase?

  • Sue Thomason

    Hi Andy i have high blood pressure on and off doc said it was stress related. Rotton hay fever said my lungs were clear. But allergies cause my bronchal tubes loads of probs. Spring and summer am dosed up with. Drops.sprays. inhaler. As a day outside i just cough and cannot breathe. Would either S ot N help me to clear my bronchial tubes. Central heating and dust etc do the same in winter. My nose is stuffed up 24/7. All my GP offers is preventive inhaler but doesnt give relief for long. Plus antibiotics kill me. And have made my immune system attack me. Your advice would be great. I have immunity to just about everything and carry a do not give card. As any injections make me pufg up like a puffer fish. Help xx Sue

  • Danny Colaco

    I am Danny
    My mother is 64 age, weight about 61 kg height 5.1 inch, suffering from Lung Cancer 4th stage with plural effusion and now for plueral effusion she is under treatment , at present she is done with ICD and now once fluid will get lesson Doctor will inject bleomycin injection IP so that the fluid will not accumulate again. I just wanted to know can I start giving her serrapeptase, will this help. Please give your valuable suggestion.

  • Tracy Cathers

    I started using serrapeptace about a year ago for carpal tunnel in both hands. It works very well and I suggested to my brother who also has carpal tunnel to try it. It’s been very affective for him also. I’m trying to order more and have found two different kinds with either 500 mg or 80,000 to 120,000 IUs. I can’t seem to find out which kind is strongest. How do I tell? I can’t find a conversion chart for serrapeptace.

  • Marie

    I purchased Serrapeptase that is labeled 5 mg dosage. I see that the majority of this enzyme is labeled in SU or SPU. I cannot find anywhere online that tells me how many SU’s or SPU’s my product contains. How do I know how much to take? Thank you.

  • Hank W

    You write, “I recommend that you EITHER use enteric coated serrapeptase…”
    But don’t say OR WHAT! “Either enteric coated … OR – what”? Please advise.

    I have already bought serrapeptase which is not enteric coated but it says it is “targeted release” — but if it is true that the stomach acid destroys it then it is a useless product, yes?

    Thank you!

  • Laura Dawn

    HI Andy. I really want to try Serrrapeptase for my 4 year old that is having bronchial issues. But she’s too young to swallow a pill. Can I open one into a glass of juice and give it to her? Will it still work like that? Thanks so much in advance for any advice you can give!

  • Mark Spires

    Hey there Andy , Mark here . While doing research on Serrapeptase I found your web site . Very informative . Glad your neck problem was taken care of . Orthopedic surgeon wanted to remove C3-C7 from my neck in 2009 . Then install a temporary titanium brace while new discs were grown via stem cell materials grafted from my femur , mixed with space age polymers . It all sounded too much like Star Trek to me . I opted out . Exercise was key in ” No cut recovery ” . My Serrapeptase question is : In 2011 I had my Gallbladder removed . From what I was told the bile duct was folded over and double clamped . Scar tissue was to grow around it and secure in place . I am taking Nattokinase and Serrapeptase for suspected DVT and poor leg circulation . In your estimation will the bile duct clamps suffer integrity from the Enzymes ?


    Every supplier of serrapeptase issues the SAME admonition: “When taking serrapeptase be sure to wait at least 2 hours from last eating and at least 1 hour from next eating.” This is to make sure the serrapeptase gets to the small intestine before the stomach acids render it useless. This is sound advice.

    Here is my question. Would I be doing anything detrimental to the serrapeptase by mixing a little baking soda with the water I use to ingest the serrapeptase? This water would serve 2 purposes: 1. To act as the transport agent to get the serrapeptase into the stomach. 2. The baking soda/water would neutralize the stomach acids from attacking the serrapeptase.

    This seems logical to me. What do you think?