Serrapeptase comparable to anti-inflammatory activity of diclofenac

In a paper published in the 2010 Jul-Dec edition of the Journal of Pharmacology & Pharmacotherapeutics, researchers compared the anti-inflammatory activity of serrapeptase (also called serratiopeptidase) and diclofenac sodium in albino rats.

Diclofenac is a nonsteroidal anti-inflammatory drug marketed under a number of names including Voltarol, Fenac, Zolterol and many others.  See Wikipedia for a more complete list.

In the study, the researchers induced acute inflammation in the rats by injecting formalin in both hind paws.

Paw volume was measured after the injection.  The rats were orally treated with either serrapeptase, diclofenac or given distilled water (control group).

Serrapeptase was found to significantly inhibit acute inflammation.  It was comparable in it’s effects to the diclofenac.  In addition, higher doses of serrapeptase were more effective in the inhibition of inflammation.

The fact that the serrapeptase was administered orally is good news for anyone taking serrapeptase as a supplement.  Many people have argued that it would be broken up and rendered useless in the gut, but this study shows that oral serrapeptase is effective.

The biggest problem with this study is the small sample size.  However, the results are still impressive.

Read the paper here.

About Andy

I suffered a serious neck injury when I was about 19 years old. That problem didn't affect me until I was in my 40s, but I then suffered two prolapsed discs in my neck and problems with my right arm and hand. Serrapeptase was recommended by my chiropractor to try to break up the scar tissue around the vertebrae that were causing me the problems. It seemed to help me with my problem, so created this site to help inform people what serrapeptase is, what it can do and just as importantly, what it cannot do. I hope you find the information useful.

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