Serrapeptase is an anti-inflammatory that is now being prescribed by more doctors. Inflammation is the part of the bodies response to damage. In this award winning video produced by Pfizer, the complexities of inflammation and autoimmune diseases are discussed.
- Our immune system protects us against intruders like bacteria and viruses.
- The skin is a major wall of defense and damage to the skin can allow bacteria and viruses access.
- Our body detects the bacteria and initiates and immune response where cells including the white blood cells try to kill the intruders. This is the inflammatory response.
- White blood cells called macrophages identify the bacteria as non-self and engulf it, and destroyed by breaking it up into little pieces.
- The little pieces are then made visible on the outer surface of the macrophage. Other immune cells can then detect that an intruder is in the body. The macrophage also releases cytokines (inflammatory substances). These cytokines bind to receptors on cells to communicate with those cells. The cytokines tell these other cells that a bacteria is present.
- More macrophages are produced to fight the infection.
- Macrophages go to the lymph nodes in the body to warn against the infection. These are information centers where immune cells meet to exchange information.
- Macrophages come into contact with T-Cells in the lymph nodes. B cells are also in the lymph nodes. T-cells recognize the pieces of bacteria on the surface of the macrophages and bind to them.
- T-cells and b-cells become active and start to divide, producing more. These cells go to the location of the infection. T-cells help other immune cells to attack the bacteria, and more cytokines are released.
- When all bacteria are destroyed, the inflammatory response ends.
- In auto-immune diseases, cells of your body come under attack in the same way that a non-self cell would.
- Self-cells are attacked and damaged. Our body produces more cells to replace those being attacked which are in turn attacked. This causes inflammation to continue leading to a chronic inflammatory response.