In a study in the Jan-Feb 2008 edition of Molecular Pharmaceutics, researchers studies whether or not liposomes could help with the oral delivery of proteins like serrapeptase. A liposome is an artificially prepared “bubble” whose surface is made of a lipid bilayer. This is very similar to the structure of our own cell membranes. Liposomes are used for drug delivery in other cases quite successfully.
The researchers compared the permeability & absorption of pure serrapeptase against liposomal formulations containing the enzyme. Their results showed that incorporating the enzyme in liposomes did indeed improve the permeability and absorption of serrapeptase. Liposome are therefore a potential delivery method for oral administration of this enzyme.
Read the article here.