Can Nattokinase Prevent Clotting In Vivo?

Nattokinase has been shown to prevent the formation of clots in vitro, that means in a test-tube.  However, the question remained, can it do the same thing in vivo (inside a living organism).

In an article in Acta Haematologica, Japanese researchers from the Nagasaki International University injected nattokinase into the tails of rats and found that it exhibited significant anti-clotting effects.

They concluded that nattokinase does have anti-thromobtic effects inside the living organism.


In vivo evaluation method of the effect of nattokinase on carrageenan-induced tail thrombosis in a rat model.

Kamiya S, Hagimori M, Ogasawara M, Arakawa M.

Acta Haematol. 2010;124(4):218-24. Epub 2010 Nov 13.

About Andy

I suffered a serious neck injury when I was about 19 years old. That problem didn't affect me until I was in my 40s, but I then suffered two prolapsed discs in my neck and problems with my right arm and hand. Serrapeptase was recommended by my chiropractor to try to break up the scar tissue around the vertebrae that were causing me the problems. It seemed to help me with my problem, so created this site to help inform people what serrapeptase is, what it can do and just as importantly, what it cannot do. I hope you find the information useful.

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